Title: Publications by unit
Subtitle:
Author:

Publications from this research unit

This page shows only publications with IRC as the affiliation of at least one author.
Publications by IRC members mentioning other affiliations are not in our database. Sorry.
See "Extra muros" papers of the units.

For copyright reasons, PDF-versions of our publications are available on the intranet only (login required  ). If you would like to receive a reprint of an IRC paper, please copy/paste the reference in the
reprint request form 


Gurumurthy, CB, O'Brien, AR, Quadros, RM, Adams, J, Jr., Alcaide, P, Ayabe, S, Ballard, J, Batra, SK, Beauchamp, MC, Becker, KA, Bernas, G, Brough, D, Carrillo-Salinas, F, Chan, W, Chen, H, Dawson, R, DeMambro, V, D'Hont, J, Dibb, K, et al..
Response to correspondence on "Reproducibility of CRISPR-Cas9 methods for generation of conditional mouse alleles: a multi-center evaluation"
Genome Biol 22, 99, 2021. (Epub 2021 Apr 7)

Van Hove, L, Lecomte, K, Roels, J, Vandamme, N, Vikkula, HK, Hoorens, I, Ongenae, K, Hochepied, T, Donati, G, Saeys, Y, Quist, SR, Watt, FM, van Loo, G, Hoste, E.
Fibrotic enzymes modulate wound-induced skin tumorigenesis
EMBO Rep , e51573, 2021. (Epub 2021 Mar 29)

Martens, A, Priem, D, Hoste, E, Vetters, J, Rennen, S, Catrysse, L, Voet, S, Deelen, L, Sze, M, Vikkula, H, Slowicka, K, Hochepied, T, Iliaki, K, Wullaert, A, Janssens, S, Lamkanfi, M, Beyaert, R, Armaka, M, Bertrand, MJM, et al..
Two distinct ubiquitin-binding motifs in A20 mediate its anti-inflammatory and cell-protective activities
Nat Immunol 21, 381-387, 2020. (Epub 2020 Mar 16)

Van Nuffel, E, Staal, J, Baudelet, G, Haegman, M, Driege, Y, Hochepied, T, Afonina, IS, Beyaert, R.
MALT1 targeting suppresses CARD14-induced psoriatic dermatitis in mice
EMBO Rep 21, e49237, 2020. (Epub 2020 Apr 28)

Andries, V, De Keuckelaere, E, Staes, K, Hochepied, T, Taminau, J, Lemeire, K, Birembaut, P, Berx, G, van Roy, F.
A new mouse model to study the role of ectopic Nanos3 expression in cancer
BMC Cancer 19, 598, 2019. (Epub 2019 Jun 17)

Demeyer, A, Skordos, I, Driege, Y, Kreike, M, Hochepied, T, Baens, M, Staal, J, Beyaert, R.
MALT1 Proteolytic Activity Suppresses Autoimmunity in a T Cell Intrinsic Manner
Front Immunol 10, 1898, 2019. (Epub 2019 Aug 14)

Gurumurthy, CB, O'Brien, AR, Quadros, RM, Adams, J, Jr., Alcaide, P, Ayabe, S, Ballard, J, Batra, SK, Beauchamp, MC, Becker, KA, Bernas, G, Brough, D, Carrillo-Salinas, F, Chan, W, Chen, H, Dawson, R, DeMambro, V, D'Hont, J, Dibb, KM, et al..
Reproducibility of CRISPR-Cas9 methods for generation of conditional mouse alleles: a multi-center evaluation
Genome Biol 20, 171, 2019. (Epub 2019 Aug 26)

Janela, B, Patel, AA, Lau, MC, Goh, CC, Msallam, R, Kong, WT, Fehlings, M, Hubert, S, Lum, J, Simoni, Y, Malleret, B, Zolezzi, F, Chen, J, Poidinger, M, Satpathy, AT, Briseno, C, et al., Vanhoutte, L, Guilliams, M, et al.
A Subset of Type I Conventional Dendritic Cells Controls Cutaneous Bacterial Infections through VEGFalpha-Mediated Recruitment of Neutrophils
Immunity 50, 1069-1083, 2019. (Epub 2019 Mar 26)

Pieters, T, T'Sas, S, Demoen, L, Almeida, A, Haenebalcke, L, Matthijssens, F, Lemeire, K, D'Hont, J, Van Rockeghem, F, Hochepied, T, Lintermans, B, Reunes, L, Lammens, T, Berx, G, Haigh, JJ, Goossens, S, Van Vlierberghe, P.
Novel strategy for rapid functional in vivo validation of oncogenic drivers in haematological malignancies
Sci Rep 9, 10577, 2019. (Epub 2019 Jul 22)

Bouhy, D, Juneja, M, Katona, I, Holmgren, A, Asselbergh, B, De Winter, V, Hochepied, T, Goossens, S, Haigh, JJ, Libert, C, Ceuterick-de Groote, C, Irobi, J, Weis, J, Timmerman, V.
A knock-in/knock-out mouse model of HSPB8-associated distal hereditary motor neuropathy and myopathy reveals toxic gain-of-function of mutant Hspb8
Acta Neuropathol 135, 131-148, 2018. (Epub 2017 Aug 5)

De Clercq, S, Keruzore, M, Desmaris, E, Pollart, C, Assimacopoulos, S, Preillon, J, Ascenzo, S, Matson, CK, Lee, M, Nan, X, Li, M, Nakagawa, Y, Hochepied, T, Zarkower, D, Grove, EA, Bellefroid, EJ.
DMRT5 Together with DMRT3 Directly Controls Hippocampus Development and Neocortical Area Map Formation
Cereb Cortex 28, 493-509, 2018. (Epub 2016 Dec 27)

Lazzarano, S, Kucka, M, Castro, JPL, Naumann, R, Medina, P, Fletcher, MNC, Wombacher, R, Gribnau, J, Hochepied, T, Van Montagu, M, Libert, C, Chan, YF.
Genetic mapping of species differences via in vitro crosses in mouse embryonic stem cells
Proc Natl Acad Sci U S A 115, 3680-3685, 2018. (Epub 2018 Mar 21)

Vanheerswynghels, M, Toussaint, W, Schuijs, M, Vanhoutte, L, Killeen, N, Hammad, H, Lambrecht, BN.
The Generation and Use of Allergen-Specific TCR Transgenic Animals
Methods Mol Biol 1799, 183-210, 2018. (Epub 2018 Jun 29)

Devos, M, Gilbert, B, Denecker, G, Leurs, K, Mc Guire, C, Lemeire, K, Hochepied, T, Vuylsteke, M, Lambert, J, Van Den Broecke, C, Libbrecht, L, Haigh, J, Berx, G, Lippens, S, Vandenabeele, P, Declercq, W.
Elevated DeltaNp63alpha levels facilitate epidermal and biliary oncogenic transformation
J Invest Dermatol 137, 494-505, 2017. (Epub 2016 Oct 7)

Pieters, T, Haenebalcke, L, Bruneel, K, Vandamme, N, Hochepied, T, van Hengel, J, Wirth, D, Berx, G, Haigh, JJ, van Roy, F, Goossens, S.
Structure-function Studies in Mouse Embryonic Stem Cells Using Recombinase-mediated Cassette Exchange
J Vis Exp , 122, 2017. (Epub 2017 Apr 27)

Steeland, S, Van Ryckeghem, S, Van Imschoot, G, De Rycke, R, Toussaint, W, Vanhoutte, L, Vanhove, C, De Vos, F, Vandenbroucke, RE, Libert, C.
TNFR1 inhibition with a Nanobody protects against EAE development in mice
Sci Rep 7, 13646, 2017. (Epub 2017 Oct 20)

Van Opdenbosch, N, Van Gorp, H, Verdonckt, M, Saavedra, PHV, de Vasconcelos, NM, Goncalves, A, Vande Walle, L, Demon, D, Matusiak, M, Van Hauwermeiren, F, D'Hont, J, Hochepied, T, Krautwald, S, Kanneganti, TD, Lamkanfi, M.
Caspase-1 Engagement and TLR-Induced c-FLIP Expression Suppress ASC/Caspase-8-Dependent Apoptosis by Inflammasome Sensors NLRP1b and NLRC4
Cell Rep 21, 3427-3444, 2017. (Epub 2017 Dec 19)

Bouhy, D, Geuens, T, De Winter, V, Almeida-Souza, L, Katona, I, Weis, J, Hochepied, T, Goossens, S, Haigh, J, Janssens, S, Timmerman, V.
Characterization of New Transgenic Mouse Models for Two Charcot-Marie-Tooth-Causing HspB1 Mutations using the Rosa26 Locus
Journal of Neuromuscular Diseases 3, 183-200, 2016. (Epub 2016 May 27)

Carceller, E, Ballegeer, M, Deckers, J, Riccardi, C, Bruscoli, S, Hochepied, T, Libert, C, Perez, P.
Overexpression of Glucocorticoid-induced Leucine Zipper (GILZ) increases susceptibility to Imiquimod-induced psoriasis and involves cutaneous activation of TGF-beta1
Sci Rep 6, 38825, 2016. (Epub 2016 Dec 9)

Hobai, IA, Aziz, K, Buys, ES, Brouckaert, P, Siwik, DA, Colucci, WS.
Distinct Myocardial Mechanisms Underlie Cardiac Dysfunction in Endotoxemic Male and Female Mice
Shock 46, 713-722, 2016. (Epub 2016 Jul 11)

Kuchmiy, AA, D'Hont, J, Hochepied, T, Lamkanfi, M.
NLRP2 controls age-associated maternal fertility
J Exp Med 213, 2851-2860, 2016. (Epub 2016 Nov 23)

Pieters, T, Goossens, S, Haenebalcke, L, Andries, V, Stryjewska, A, De Rycke, R, Lemeire, K, Hochepied, T, Huylebroeck, D, Berx, G, Stemmler, MP, Wirth, D, Haigh, JJ, van Hengel, J, van Roy, F.
p120 Catenin-Mediated Stabilization of E-Cadherin Is Essential for Primitive Endoderm Specification
PLoS Genet 12, e1006243, 2016. (Epub 2016 Aug 24)

Thoonen, R, Cauwels, A, Decaluwe, K, Geschka, S, Tainsh, RE, Delanghe, J, Hochepied, T, De Cauwer, L, Rogge, E, Voet, S, Sips, P, Karas, RH, Bloch, KD, Vuylsteke, M, Stasch, JP, Van de Voorde, J, Buys, ES, Brouckaert, P.
Cardiovascular and pharmacological implications of haem-deficient NO-unresponsive soluble guanylate cyclase knock-in mice
Nat Commun 6, 8482, 2015. (Epub 2015 Oct 7)

Van Overbeke, W, Wongsantichon, J, Everaert, I, Verhelle, A, Zwaenepoel, O, Loonchanta, A, Burtnick, LD, De Ganck, A, Hochepied, T, Haigh, J, Cuvelier, C, Derave, W, Robinson, RC, Gettemans, J.
An ER-directed gelsolin nanobody targets the first step in amyloid formation in a gelsolin amyloidosis mouse model
Hum Mol Genet 24, 2492-507, 2015. (Epub 2015 May 1)

Guilliams, M, De Kleer, I, Henri, S, Post, S, Vanhoutte, L, De Prijck, S, Deswarte, K, Malissen, B, Hammad, H, Lambrecht, BN.
Alveolar macrophages develop from fetal monocytes that differentiate into long-lived cells in the first week of life via GM-CSF
J Exp Med 210, 1977-1992, 2013. (Epub 2013 Sep 16)

Osorio, F, Lambrecht, B, Janssens, S.
The UPR and lung disease
Semin Immunopathol 35, 293-306, 2013. (Epub 2013 Mar 28)

Plantinga, M, Guilliams, M, Vanheerswynghels, M, Deswarte, K, Branco-Madeira, F, Toussaint, W, Vanhoutte, L, Neyt, K, Killeen, N, Malissen, B, Hammad, H, Lambrecht, BN.
Conventional and monocyte-derived CD11b(+) dendritic cells initiate and maintain T Helper 2 cell-mediated immunity to house dust mite allergen
Immunity 38, 322-335, 2013. (Epub 2013 Jan 22)

Vanhooren, V, Vandenbroucke, RE, Dewaele, S, Van Hamme, E, Haigh, J, Hochepied, T, Libert, C.
Mice overexpressing beta-1,4-galactosyltransferase I are resistant to TNF-induced inflammation and DSS-induced colitis
PLoS One 8, e79883, 2013. (Epub 2013 Dec 5)

Vyas, R, Kumar, R, Clermont, F, Helfricht, A, Kalev, P, Sotiropoulou, P, Hendriks, IA, Radaelli, E, Hochepied, T, Blanpain, C, Sablina, A, van Attikum, H, Olsen, JV, Jochemsen, AG, Vertegaal, ACO, Marine, JC.
RNF4 is required for DNA double-strand break repair in vivo
Cell Death Differ 20, 490-502, 2013. (Epub 2012 Nov 30)

Pieters, T, Haenebalcke, L, Hochepied, T, D'Hont, J, Haigh, JJ, van Roy, F, van Hengel, J.
Efficient and user-friendly pluripotin-based derivation of mouse embryonic stem cells
Stem Cell Rev Rep 8, 768-778, 2012. (Epub 2011 Oct 20)

Migliorini, D, Bogaerts, S, Defever, D, Vyas, R, Denecker, G, Radaelli, E, Zwolinska, A, Depaepe, V, Hochepied, T, Skarnes, WC, Marine, JC.
Cop1 constitutively regulates c-Jun protein stability and functions as a tumor suppressor in mice
J Clin Invest 121, 1329-1343, 2011. (Epub 2011 Mar 14)

Back to previous page

Export in CSV

To top

What do these icons mean?

pdf file (800 kb)


Go back to the regular design...