» Home » Education » PhD Theses 
Print this pageEmail this page URLConvert this page to PDF

PhD defences

PhD defences are open to the public, and take place in the J. Schell seminar room of the UGent-VIB research building,  (unless otherwise specified).

Please check the IRC Calendar to know more about the upcoming PhD defences.

 

IRC Ph.D. theses since 2000

 Pdf-versions of the theses are available on the IRC intranet only (login required ).


  1. Cappe Benjamin (7-July-2022 ; P. Vandenabeele & F. Riquet)
    Investigating the role of MLKL and EVs in cell-cell communication during necroptosis
  2. Pauwels Marie (28-June-2022 ; R. Vandenbroucke & L. Van Hoecke)
    Exploration of blood-cerebrospinal fluid barrier targeted extracellular vesicles as brain delivery strategy
  3. Jonckheere Sven (24-June-2022 ; G. Berx & S. Goossens)
    Therapeutic targeting of ZEB1-mediated EMT in metastatic colorectal cancer
  4. Remmerie Anneleen (13-June-2022 ; C. Scott & M. Guilliams)
    Understanding Hepatic Macrophage Phenotypes and Functions in Metabolic-Associated Fatty Liver Disease
  5. Kim Seo Woo (18-May-2022 ; R. Beyaert, J. Staal & A. Goossens)
    Unraveling the functional roles of endogenous phytohormones in mammals
  6. Holgado Muñoz Aurora (4-May-2022 ; R. Beyaert & I. Afonina)
    Targeting and regulation of interleukin-33 signalling in lung inflammation
  7. Van Coillie Samya (10-Dec-2021 ; P. Vandenabeele & T. Vanden Berghe)
    Therapeutic targeting of ferroptosis in experimental models of acute organ injury
  8. Delanghe Tom (10-Dec-2021 ; M.J. Bertrand & Y. Dondelinger)
    Unraveling the role of RIPK1 phosphorylation in TNF-mediated cell death and inflammation
  9. Vanderhaeghen Tineke (6-Dec-2021 ; C. Libert & R. Beyaert)
    The Effect of Hypoxia and Hypoxia Inducible Factors on the Glucocorticoid Receptor Function and their Role during Sepsis
  10. Srinivasan Sahana (3-Dec-2021 ; G. van Loo & M. Lamkanfi)
    Characterizing the role of microglial inflammation in neurodegeneration
  11. Oltean Teodora (30-Nov-2021 ; P. Vandenabeele, J. Maelfait & S. Adjemian Catani)
    Unraveling cell death modalities during influenza infection, vaccination, and cancer therapy
  12. Van Hove Lisette (19-Oct-2021 ; E. Hoste & G. van Loo)
    Unravelling molecular mechanisms mediating skin inflammation and tumour formation
  13. Fernandes Côrte-Real Beatriz (30-Sep-2021 ; M. Kleinewietfeld)
    The impact of high salt on Foxp3+ regulatory T cell metabolism and function
  14. Wiernicki Bartosz (27-Sep-2021 ; P. Vandenabeele, T. Vanden Berghe & K. Ravichandran)
    The role of lipid peroxidation in cell death and adaptive immune system regulation
  15. Vrancken Kurt (21-Sep-2021 ; P. Brouckaert & A. Blood)
    Plasma nitric oxide handling and its metabolism to endocrine S-nitrosothiol and nitrite: Role of ceruloplasmin and a novel function for postprandial triglyceride rich lipoproteins
  16. De Schutter Elke (8-Sep-2021 ; G. Van Camp, P. Vandenabeele & F. Riquet)
    Elucidation of the role of GSDME during apoptosis-driven secondary necrosis
  17. Percier-Lehebel Pauline (24-Aug-2021 ; W. Declercq, J. Grooten & O. Denis)
    Alternaria alternata and Aspergillus fumigatus mold species counteract experimental mycobacterial and allergic lung diseases through divergent innate immune mechanisms
  18. De Munck Steven (12-Jul-2021 ; S. Savvides)
    Structure and mechanism of cytokine mediated activation of ALK family receptor tyrosine kinases
  19. De Vos Tatjana (8-Jul-2021 ; S. Savvides)
    Structural basis for the activation and antagonism of the IL-9 signaling complex
  20. Loret Nele (08-Jun-2021 ; G. Berx, B. Lambrecht & P. Tummers)
    Cellular plasticity and heterogeneity in ovarian cancer progression and therapy resistance
  21. T'Jonck Wouter (28-Apr-2021 ; C. Scott)
    Notch-induced LXRα expression is essential for the maintenance of Kupffer cell identity
  22. Renson Thomas (15-Apr-2021 ; D. Elewaut, F. Van den Bosch & J. Dehoorne)
    Identifying pitfalls and opportunities of magnetic resonance imaging in spondyloarthritis
  23. Cloots Eva (12-Apr-2021 ; S. Janssens & S. Eyckerman)
    The ins and outs of IRE1B signaling: the role of IRE1B in mucosal homeostasis
  24. Vandewalle Jolien (24-Mar-2021 ; C. Libert & K. De Bosscher)
    The role of glucocorticoid resistance and TNFR1 signaling in sepsis
  25. Bosteels Cédric (26-Feb-2021 ; B. Lambrecht & H. Hammad)
    The role of DC subsets in respiratory viral infections and vaccination: a case of mistaken identity
  26. Vandendriessche Charysse (17-Dec-2020 ; R. Vandenbroucke & C. Van Cauwenberghe )
    Exploring the role of extracellular vesicles in Alzheimer’s and Parkinson’s disease
  27. Todorov Helena (16-Dec-2020 ; Y. Saeys & J. Marvel )
    Structure learning to unravel mechanisms of the immune system
  28. Dimitrakopoulou Dionysia (16-Oct-2020 ; K. Vleminckx & A. Willaert)
    CRISPR/Cas9 mediated modeling of TP53 and PTEN related malignancies in Xenopus tropicalis
  29. Gorlé Nina (19-Jun-2020 ; R. Vandenbroucke & F. Haesebrouck)
    Study of the importance of the choroid plexus in peripheral and brain inflammation
  30. Gilis Elisabeth (29-May-2020 ; D. Elewaut & S. Lambrecht)
    The role of MALT1 in rheumatic diseases
  31. Zuallaert Jasper (27-May-2020 ; W. De Neve, N. Callewaert & Y. Saeys)
    Automated learning of biologically relevant features from primary sequence using convolutional neural networks
  32. Priem Dario (22-Apr-2020 ; M. Bertrand)
    The ubiquitin-dependent regulation of the inflammatory response by A20 and MAGED1
  33. Van Wyngene Lise (19-Mar-2020 ; C. Libert & G. van Loo)
    The role of hepatic PPARa in sepsis and ZBTB32 in metabolic homeostasis
  34. Van Looveren Kelly (13-Mar-2020 ; C. Libert & K. De Bosscher)
    The glucocorticoid receptor in acute inflammation: new molecular insights and development of a new GR dimerization mutant
  35. Martens Arne (11-Feb-2020 ; G. van Loo)
    Mechanistic insights into the regulation of inflammatory pathology by A20
  36. Cannoodt Robrecht (16-Dec-2019 ; Y. Saeys & K. De Preter)
    Modelling single-cell dynamics with trajectories and gene regulatory networks
  37. Debeuf Nincy (13-Dec-2019 ; B. Lambrecht & S. Janssens)
    ORMDL3 in the regulation of sphingolipid synthesis and in the pathogenesis of allergic asthma
  38. Detry Sammy (9-Dec-2019 ; S. Savvides & Y. Bloch)
    Unraveling and targeting of molecular signaling mechanisms of IL-12 family, IL-18 and IL-33 cytokines using integrative structural biology
  39. Saelens Wouter (24-Oct-2019 ; Y. Saeys & B. Lambrecht)
    Developing and benchmarking methods for analysing transcriptomics data
  40. Brkic Marjana (27-Sep-2019 ; R. Vandenbroucke, S. Kanazir & C. Libert)
    Studies on structural and functional changes of mouse choroid plexus in the initiation of neuroinflammation
  41. Dubois Hanne (17-Sep-2019 ; A. Wullaert & M. Lamkanfi)
    Characterisation of innate immune responses associated with gastrointestinal norovirus infection
  42. Vanderkerken Matthias (16-Sep-2019 ; B. Lambrecht & T. Kerre)
    Molecular interactions controlling immune homeostasis in the marginal zone
  43. Bauwens Eva (3-Sep-2019 ; R. Vandenbroucke, F. Haesebrouck, A. Smet)
    Impact of gastric Helicobacter infections on the stomach-brain axis
  44. Martens Sofie (4-Jul-2019 ; P. Vandenabeele, V. Goossens, N. Takahashi)
    Necroptotic proteins in diseases: targeting RIP kinases in inflammatory disorders and exploring the role of MLKL in melanoma development
  45. Sabaghian Ehsan (1-Jul-2019 ; Y. van de Peer & Y. Saeys)
    Unravelling gene functions in Arabidopsis thaliana by means of network biology and machine learning
  46. Van Nuffel Elien (27-Jun-2019 ; R. Beyaert & I. Afonina)
    CARD14/MALT1 signaling in skin homeostasis and disease
  47. Naert Thomas (21-Jun-2019 ; K. Vleminckx)
    CRISPR/Cas9-mediated cancer modeling and identification of cancer cell vulnerabilities in Xenopus tropicalis
  48. Bolli Evangelia (19-Jun-2019 ; J. Van Ginderachter)
    Nanobody-mediated targeting of tumor-associated macrophages for cancer therapy
  49. Cambré Isabelle (4-Jun-2019 ; D. Elewaut & S. Lambrecht)
    Mechanical strain and its implications for mouse and human rheumatic diseases
  50. De Smedt Eva (23-May-2019 ; G. Berx)
    ZEB1 as 'jack-of-all-trades' in breast cancer progression
  51. Roels Joris (3-May-2019 ; Y. Saeys & W. Philips)
    Automated Segmentation of 3D Electron Microscopy Images
  52. Voet Sofie (15-Mar-2019 ; G. van Loo)
    Study of inflammatory signaling and microglia activation in central nervous system pathology
  53. Lork Marie Therese (8-Mar-2019 ; R. Beyaert, J. Staal)
    Molecular regulation of T cell receptor signaling
  54. Vandersarren Lana (27-Feb-2019 ; S. Janssens, B. Lambrecht)
    ER stress and T cell biology: IRE1 signaling and TAOK3 function
  55. Haspeslagh Eline (14-Feb-2019 ; H. Hammad, B. Lambrecht)
    Pulmonary immunomodulation of house dust mite-induced allergic asthma
  56. Pannecoucke Erwin (14-Feb-2019 ; S. Savvides)
    An integrative approach towards unraveling the activation of oncogenic FLT3
  57. Pauwels Anne-Marie (7-Jan-2019 ; R. Beyaert, Hoffmann E.)
    Impact of TLR4 engagement on the phagosomal proteome in dendritic cells and consequences for antigen degradation and presentation
  58. Mamantopoulos Michail (19-Dec-2018 ; A. Wullaert, M. Lamkanfi)
    Inflammasomes in intestinal host-microbe interactions
  59. Timmermans Steven (11-Dec-2018 ; C. Libert, Y. Saeys)
    Identifying and classifying protein coding gene polymorphisms between laboratory mouse strains and investigating glucocorticoid actions in sepsis models
  60. Souffriau Jolien (7-Dec-2018 ; C. Libert)
    Targeting TNF-induced acute inflammation by making use of SEDIGRAM or zinc
  61. Fulara Aleksandra (7-Dec-2018 ; S. Savvides)
    Study of the GspLM complex, an inner membrane component of the type II secretion system from Pseudomonas aeruginosa
  62. Vluymans Sarah (29-June-2018 ; Y. Saeys, C. Cornelis)
    Dealing with Imbalanced and Weakly Labelled Data in Machine Learning using Fuzzy and Rough Set Methods
  63. Godar Marie (29-June-2018 ; B. Lambrecht, C. Blanchetot)
    Development of Novel Multifunctional Antibodies to Treat Asthma
  64. Saavedra Pedro H. V. (26-June-2018 ; A. Wullaert, M. Lamkanfi)
    Mechanism and functions of the cytosolic receptor Pyrin
  65. Moraes de Vasconcelos Nathalia (26-June-2018 ; A. Wullaert, M. Lamkanfi)
    Cell death signaling at the crossroads of inflammasome activation
  66. Slowicka Karolina (21-June-2018 ; G. van Loo, L. Vereecke)
    Study of intestinal homeostasis and pathology through mouse gene targeting
  67. Soen Bieke (30-May-2018 ; G. Berx)
    Zeb1 and Zeb2: master regulators of mononuclear phagocyte development and homeostasis
  68. De Keuckelaere Evi (22-May-2018 ; F. Van Roy, G. Berx)
    The role of Nanos3 in tumor progression
  69. Kip Elodie (9-May-2018 ; R. Beyaert, S. De Gucht)
    Impact of the paracaspase MALT1 on rabies virus-induced neuroinflammation and disease
  70. Sundararaman Srividhya (26-Apr-2018 ; F. Van Roy, K. Vleminckx)
    Cadherin repertoires in lower metazoans - Trichoplax adhaerens and Nematostella vectensis
  71. Bloch Yehudi (16-Apr-2018 ; S. Savvides, K. Verstraete)
    Structure, mechanism, and antagonism of the pro-inflammatory receptor complex mediated by interleukin-23
  72. Carron Philippe (30-Mar-2018 ; D. Elewaut, F. Van den Bosch)
    New Imaging modalities and treatment strategies in Spondyloarthritis
  73. Delvaeye Tinneke (9-Mar-2018 ; P. Vandenabeele, D. Krysko, L. Leybaert)
    The pathological role of Cx43 and MLKL in TNF-induced Systemic Inflammatory Response Syndrome
  74. Noelanders Rivka (1-Mar-2018 ; K. Vleminckx)
    Wnt/beta-catenin signaling in the Xenopus hindbrain: development and cancer
  75. Tanghe Giel (23-Feb-2018 ; W. Declercq)
    Mechanistic insights into the regulation of RIPK4 and its function in skin homeostasis and pathology
  76. Berings Margot (21-Feb-2018 ; M. Dullaers, P. Gevaert, B. Lambrecht)
    House dust mite allergic rhinitis: A novel take on diagnosis and treatment
  77. Varkas Gaëlle (20-Feb-2018 ; D. Elewaut, F. Van den Bosch)
    Axial spondyloarthritis: New insights in diagnosis and patient stratification
  78. D'hondt Sanne (15-Dec-2017 ; F. Malfait, S. Janssens & M. Bertrand)
    Type III collagen, a major fibrillar collagen with major issues
  79. Dendoncker Karen (13-Oct-2017 ; C. Libert)
    Elucidating the mechanism behind TNF-induced glucocorticoid resistance and strategies to overcome this resistance
  80. Steeland Sophie (5-Oct-2017 ; C. Libert & R. Vandenbroucke)
    Therapeutic targeting of inflammatory mediators in sepsis and neurodegenerative diseases
  81. Favreau Mérédis (4-Oct-2017 ; D. Elewaut, K. Venken, E. Menu & K. Vanderkerken)
    Immune therapy in multiple myeloma: Can iNKT cells be targeted?
  82. Abels Chloé (26-Sep-2017 ; J. Van Ginderachter, P. De Baetselier & A. Beschin)
    Unravelling the role of liver associated myeloid cells in sterile inflammation and infection
  83. De Wilde Katelijne (20-Sep-2017 ; D. Elewaut & S. Lambrecht)
    Novel myeloid regulators of rheumatic diseases
  84. Bogaert Delfien (4-Sep-2017 ; M. Dullaers, F. Haerynck & E. De Baere)
    Molecular diagnosis of Common Variable Immunodeficiency and related antibody disorders: an integrated immunological and genetic approach
  85. Van der Borght Katrien (7-Jul-2017 ; B. Lambrecht)
    Cardiac dendritic cells activate autoreactive T cells in the healthy and diseased heart
  86. Deckers Julie (5-Jul-2017 ; H. Hammad & K. De Bosscher)
    The skin as a central player in house dust mite allergy
  87. Aaes Tania Love (5-Jul-2017 ; P. Vandenabeele & D. Krysko)
    The impact of cell death modalities on the immunogenicity of cancer cells
  88. Vandamme Niels (26-Jun-2017 ; G. Berx)
    ZEB1 and ZEB2 dictate melanocyte homeostasis and melanoma phenotype switching
  89. Ruyssinck Joerie (19-Jun-2017 ; Y. Saeys & T. Dhaene)
    Machine Learning for Biological Network Inference
  90. Krols Michiel (13-Jun-2017 ; S. Janssens & V. Timmerman)
    Mutations in Atlastin-3: implications for ER membrane fusion and crosstalk with mitochondria
  91. Le Cann Fabienne (2-Jun-2017 ; P. Vandenabeele)
    Characterization of new necroptosis innhibitors targeting RIPK1
  92. Udhayakumar Vimal Kumar (24-May-2017 ; J. Grooten & S. De Koker)
    Development and validation of synthetic-virus like vaccines
  93. Van Gassen Sofie (23-May-2017 ; Y. Saeys & T. Dhaene)
    Development of Machine learning techniques for flow cytometry data
  94. Govindarajan Srinath (16-May-2017 ; D. Elewaut & M. Drennan)
    Mechanistic insights into the regulation of iNKT development and cytokine production
  95. Schuijs Martijn (14-Apr-2017 ; H. Hammad and B. Lambrecht)
    The Pathogenesis of House Dust Mite-driven Asthma: From Barn to Bedside
  96. Ladik Maria (4-Apr-2017 ; P. Vandenabeele)
    Development of biosensing systems to monitor necroptosis
  97. Van Nieuwenhuysen Tom (31-Mar-2017 ; K. Vleminckx)
    Modeling human disease in Xenopus tropicalis using programmable nucleases
  98. Urwyler-Rösselet Corinne (17-Mar-2017 ; W. Declercq & P. Vandenabeele)
    Study of the functions of RIPK4 in epidermal development and signal transduction
  99. Balusu Sriram (15-Mar-2017 ; R. Vandenbroucke & C. Libert & K. Gevaert)
    Novel insights into the choroid plexus response to systemic inflammation and Alzheimer's disease
  100. Vermeulen Ilke (3-Mar-2017 ; J. Grooten)
    Tuberculosis: how different synthetic analogues of pathogen associated mycolates affect lipid homeostasis of murine host macrophages
  101. Catrysse Leen (24-Feb-2017 ; G. van Loo & R. Beyaert)
    Diabetes and inflammation, how A20 regulates tissue homeostasis in metabolic tissues
  102. Sichien Dorine (24-Feb-2017 ; B. Lambrecht & M. Guilliams)
    Differential requirement for IRF8 in the development and function of monocytes and dendritic cells
  103. Tavernier Simon (31-Jan-2017 ; B. Lambrecht & S. Janssens)
    Dendritic cells under stress: on the role of the unfolded protein response and hypoxia signalling
  104. Cypers Heleen (23-Jan-2017 ; D. Elewaut)
    The role of intestinal inflammation in initiation, monitoring and outcome of spondyloarthritis
  105. De Beuckelaer Ans (23-Dec-2016 ;J. Grooten)
    mRNA-based vaccines to elicit CD8 T cell immunity
  106. Borghi Alice (22-Dec-2016 ;R. Beyaert)
    New insight into the ubiquitin-mediated regulation of TNFR2 signaling
  107. Hassannia Behrouz (22-Dec-2016 ;P. Vandenabeele)
    Ferroptosis: triggers, inhibitors and therapeutic potential in neuroblastoma
  108. Van Putte Wouter (19-Dec-2016 ;S. Savvides)
    The type II secretion system and membrane vesiculation: bacterial secretion systems as a target for anti-virulence drug development
  109. Meloni Laura (8-Dec-2016 ;R. Beyaert)
    Molecular mechanisms of mechanotransdcution and osteoclastogenesis in arthritis
  110. Gül Ismail Sahin (6-Dec-2016 ;F. Van Roy)
    Molecular evolution of the armadillo repeat superfamily and characterization of representative members in key model organisms
  111. Demeestere Delphine (2-Dec-2016 ;C. Libert & R. Vandenbroucke)
    A study of inflammatory mechanisms involved in systemic inflammation and brain trauma
  112. Ballegeer Marlies (2-Dec-2016 ;C. Libert & R. Vandenbroucke)
    Study of the role and regulation of Glucocorticoid induced leucine zipper (GILZ) and GR dimers in acute inflammation
  113. Neyt Katrijn (21-Oct-2016 ;B. Lambrecht & M. Guilliams)
    Pulmonary immune responses against influenza A virus infection
  114. Jimenez Fernandez Daniel (22-Sep-2016 ;L. Lamkanfi & K. Gevaert)
    Functional characterization of inflammatory caspases
  115. Billi Eleonora (22-Sep-2016 ; F. Van Roy & J. Tavernier)
    Identification and functional analysis of molecular interaction partners of δ-protocadherin family members with putative roles in cancer
  116. Sips Magdalena (31-Aug-2016 ; P. Brouckaert)
    Harnessing innate immunity to prevent and control HIV infection
  117. Demeyer Annelies (28-Jun-2016 ; R. Beyaert)
    Functional characterization of the paracaspase MALT1 in T cells
  118. Grootjans Sasker (15-Apr-2016 ; P. Vandenabeele)
    Identification of potential RIPK1 substrates during Necroptosis
  119. Aguileta Miguel (15-Apr-2016 ; M. Bertrand & P. Vandenabeele)
    Characterization of new proteins involved in apoptosis regulation
  120. Juchtmans Nele (22-Mar-2016 ; D. Elewaut)
    The role of stress related proteins in osteoarthritis
  121. Félix Jan (7-Jan-2016 ; S. Savvides)
    Structural Principles of binding duality in cognate and viral cytokine receptors
  122. Petta Ioanna (4-Dec-2015 ; C. Libert & J. Tavernier)
    Identification of striatin-3 and ZBTB32 as two novel modulators of glucocorticoid receptor activity
  123. Sipieter François (3-Dec-2015 ; F. Riquet, P. Vandenabeele, K. Cailliau-Maggio & L. Héliot)
    Development and validation of kinase activity reporters for the dynamical study of cell response modalities by microscopy ~ Role of the kinase MAPK/ERK in necroptosis.
  124. Deng Lei (3-Dec-2015 ; X. Saelens)
    Targeted prokaryotic delivery of a conserved influenza A virus epitope for oral vaccination
  125. Santens Francis (25-Sep-2015 ; N. Callewaert)
    Engineering of protein production systems to drastically reduce glycan heterogeneity of biopharmaceuticals
  126. Claes Katrien (11-Sep-2015 ; N. Callewaert)
    Development of modular engineering tools for membrane protein expression in yeast
  127. Dondelinger Yves (3-Jul-2015 ; P. Vandenabeele & M. Bertrand)
    Unraveling the molecular mechanisms of RIPK1-mediated cell death
  128. Vandewalle Kristof (19-Jun-2015 ; N. Callewaert)
    Building genome-wide mutant resources in slow-growing mycobacteria
  129. De Visscher Charlotte (20-Feb-2015 ; N. Callewaert)
    Engineering of the production of mannose-6-phosphate-modified lysosomal enzymes by the yeast Pichia pastoris
  130. Elton Lynn (19-Dec-2014 ; R. Beyaert)
    Identification and functional characterization of novel MALT1 substrates
  131. Smet Muriel (18-Dec-2014 ; J. Grooten)
    Cholesterol-sensing liver X receptors and mycolic acid bio-lipids at the crossroads of lipid metabolism and inflammation
  132. Mueller Christina (16-Dec-2014 ; R. Beyaert)
    Molecular and functional characterization of interleukin-33 signaling
  133. Volckaert Thomas (8-Dec-2014 ; R. Beyaert)
    Epithelial-mesenchymal crosstalk during lung development and regeneration
  134. Grine Lynda(25-Nov-2014 ; C. Libert)
    Study of the role of type I Interferons in TNF-mediated inflammation.
  135. Tyberghein Koen (30-Sep-2014 ; F. Van Roy)
    Alpha-catenins: protein replacement as a strategy against cancer invasion and metastasis?
  136. Ydens Elke (24-Apr-2014 ; S. Janssens & V. Timmerman)
    Activation of the innate immune response during peripheral nerve degeneration: from pattern recognition receptors to immune effector cells
  137. Broos Stefan (24-Jan-2014 ; F. Van Roy & P. De Bleser)
    Developing algorithms for the in silico identification of transcription factor binding sites
  138. Vandendriessche Benjamin (13-dec-2013 ; P. Brouckaert & A. Cauwels)
    Complex dynamics in systemic inflammation: quantification of coupling and targeting of the nitric oxide-soluble guanylate cyclase axis
  139. Pollard Charlotte (6-dec-2013 ; J. Grooten & S. De Koker)
    Evaluation of CD8+ T cell responses upon mRNA vaccination and the implication of type I IFN signaling
  140. Puimège Leen (29-nov-2013 ; C. Libert)
    A molecular genetic analysis of TNFR1 regulation in SPRET/EI and generation of new TNFR1 inhibitory tools
  141. Vandevyver Sofie (22-nov-2013 ; C. Libert)
    Study of the molecular mechanisms of glucocorticoid receptor function and resistance in TNF-induced toxicity
  142. Plantinga Maud (16-Oct-2013 ; Bart Lambrecht)
    The role of dendritic cell subsets in allergic sensitization
  143. Ayiseh Rene B. (19-Sep-2013 ; P. Vandenabeele)
    Role of cell death and caspases in intestinal inflammation
  144. Kaczmarek Agnieszka (4-Jul-2013 ; P. Vandenabeele)
    Sensing of apoptotic and necroptotic cell death by the innate immune system
  145. Willart Monique (27-Jun-2013 ; B. Lambrecht)
    Immune activation at the lung epithelial barrier
  146. McGuire Conor (31-May-2013 ; G. van Loo & R. Beyaert)
    The study of signaling pathways controlling central nervous system inflammation and pathology
  147. De Baets Sarah (10-Apr-2013 ; X. Saelens)
    Novel vaccination strategies against human repiratory syncytial virus
  148. Pringels Sarah (17-Apr-2013 ; J. Grooten)
    Screening of the Vascular Endothelial Growth Factor family in human colon cancer
  149. Cardoso Francisco Miguel Lopez (28-Feb-2013 ; X. Saelens)
    Antiviral activity of camelid single domain antibodies targeting the neuraminidase of H5N1 Influenza virus
  150. De Groote Philippe (21-dec-2012 ; W. Declercq)
    Study of RIPK4 function in skin homeostatsis and disease
  151. Devos Michael (21-dec-2012 ; W. Declercq)
    Study on the role of delatNp63alpha and caspase-14 in skin homeostasis and pathology
  152. Kahr Irene (20-dec-2012 ; F. Van Roy)
    Functional analysis of the candidate tumor suppressor protein protocadherin-10
  153. Verhelst Judith (19-dec-2012 ; X. Saelens)
    Unraveling the antiviral mechanism of mouse Mx1 directed against influenza A
  154. Janssens Sylvie (19-Oct-2012 ; K. Vleminckx)
    Identification of novel target genes of the Wnt/β-catenin pathway during Xenopus development and analysis of their epigenetic regulation
  155. Haenebalcke Lieven (5-Oct-2012 ; J. Haigh)
    Generation and use of novel ROSA26-based ESC/iPSC technologies to study cellular reprogramming and gene function during lineage-directed differentiation
  156. Naessens Thomas (6-Jul-2012 ; J. Grooten)
    Functional dynamics of resident alveolar macrophages in a mouse model of allergic asthma
  157. Vander Beken Seppe (6-Jul-2012 ; J. Grooten)
    Mycobacterium tuberculosis bio-lipid mycolic acid and mammalian cholesterol-sensor liver X-receptor in airway immunity
  158. Farhang Ghahremani Morvarid (5-Jul-2012 ; J. Haigh)
    Molecular and genetic interplay between p53 and VEGF in tumour angiogenesis
  159. Meuris Leander (2-Jul-2012 ; N. Callewaert)
    GlycoDelete: a new glycoengineering concept for protein production in mammalian cells
  160. Nittner David (8-Jun-2012 ; J.C. Marine)
    Role of the microRNA pathway in retinoblastoma
  161. Guerfal Mouna (8-May-2012 ; N. Callewaert)
    Yeast secretory system engineering for enhanced membrane protein expression
  162. Roose Kenny (26-Jan-2012 ; X. Saelens)
    Design and validation of novel broad influenza B vaccine
  163. Andries Vanessa (26-Jan-2012 ; F. Van Roy)
    Functional analysis of the NBPF1 gene in cancer
  164. Bekaert Tine (20-Jan-2012 ; R. Beyaert)
    Functional characterization of the paracaspase MALT1
  165. Gembarska Agnieszka (19-Jan-2012 ; J.C. Marine)
    MDMX is a key therapeutic target in skin melanoma
  166. Schotsaert Michael (16-Dec-2011 ; X. Saelens)
    Modulation of humoral and cellular immunity to influenza by vaccination
  167. Zwolinska Aleksandra (15-Dec-2011 ; J.C. Marine)
    Study of three putative nuclear modulators of the p53 pathway
  168. Fransen Mathias (9-Dec-2011 ; K. Vleminckx)
    Exploring the role of caspases and RIPK4 during Xenopus development
  169. Van Hauwermeiren Filip (25-Nov-2011 ; C. Libert)
    New strategies to prevent TNF-induced toxicity in TNF/IFNgamma-based anti-tumor models
  170. Gheldof Alexander (21-Oct-2011 ; G. Berx)
    Functional analysis of the EMT inducing transcription factor ZEB1 during malignant carcinoma progression
  171. Duprez Linde (14-Oct-2011 ; P. Vandenabeele)
    Role of RIP1 in TNF-induced cell death in vitro and in vivo
  172. Tatari Marianthi (26-Sep-2011 ; G. Berx)
    In vivo analysis of the role of ZEB2 in epithelial homeostasis and tumor progression
  173. Pinheiro Iris (8-Jul-2011; C. Libert)
    Molecular cloning of the X-chromosome located LPS-resistance gene of SPRET/Ei mice
  174. Maelfait Jonathan (8-Jul-2011; R. Beyaert)
    Signaling in antiviral immunity and its regulation by the ubiquitin-editing protein A20
  175. Lambertz Irina (6-Jul-2011; J.C. Marine)
    MicroRNA control of cancer development
  176. Vanlangenakker Nele (1-Jul-2011; P. Vandenabeele)
    Unraveling TNF-induced necrotic signaling pathways using RNA interference and live-cell imaging
  177. Quimbaya Mauricio (23-Jun-2011; L. De Veylder & G. Berx)
    Identification of novel conserved cell cycle genes through data integration and comparative genomics between plants and humans
  178. Verhelst Kelly (17-Jun-2011; R. Beyaert)
    Molecular analysis of the ubiquitin-editing protein A20
  179. Vereecke Lars (27-May-2011; R. Beyaert)
    Controlling inflammation and cell death at the intestinal epithelial interface and beyond: Lessons from conditional 120 knockout mice
  180. De Pourcq Karen (27-May-2011; N. Callewaert)
    Glycosylation engineering in the yeast Yarrowia lipolytica: creating an expression system to produce complete homogeneous glycoproteins
  181. Wirawan Ellen (8-Apr-2011; P. Vandenabeele)
    Molecular interplay between autophagy and apoptosis through caspase-mediated cleavage of Beclin-1
  182. Kersse Kristof (8-Apr-2011; P. Vandenabeele)
    Inflammasome modulation and NF-kB activation by caspase-1-related CARD domains
  183. Dejonckheere Eline (1-Apr-2011; C. Libert)
    The role of matrix metalloproteinase 8 in TLR4-mediated acute systemic inflammation
  184. Pieters Tim (25-Feb-2011; F. Van Roy)
    Functional analysis of mice harboring a knock-out or knock-in of the alternatively spliced exon C of p120ctn
  185. Hooghe Bart (25-Feb-2011; F. Van Roy)
    In silico approaches to studying transcriptional gene regulation: prediction of transcription factor binding sites and applications thereof
  186. De Clercq Sarah (5-Jul-2010; J.-C. Marine)
    Study of the physiological and oncogenic properties of Mdm2 and Mdm4
  187. Van Bogaert Tom (1-Jul-2010; C. Libert)
    Study of the molecular mechanism of glucucorticoid resistance in tumor necrosis factor-induced systemic inflammation
  188. Galle Marlies (1-Jul-2010; R. Beyaert)
    Modulation of macrophage immune responses by the Pseudomonas aeruginosa type three secretion system
  189. Hoste Esther (24-Jun-2010; W. Declercq & P. Vandenabeele)
    Study of the role of caspase-14 in epidermal cornification
  190. Lefever Tine (3-Jun-2010; F. Van Roy)
    Analysis of N-WASP function in keratinocytes in vivo
  191. Vanderschaeghe Dieter (1-Jun-2010; J. De Langhe & N. Callewaert)
    GlycoHepatoTest: validation and analytical technology development for implementation on microfluidics analyzer
  192. Dejager Lien (30-Apr-2010; C. Libert)
    Molecular and genetic analysis of the resistance of the mouse strain SPRET/Ei to endotoxemia and Gram-negative sepsis
  193. Houthuys Erica (2-Apr-2010; P. Brouckaert)
    Transcriptome analysis of monocytes and macrophages in mycobacterial infection and chronic kidney disease
  194. Thoonen Robrecht (26-Feb-2010; P. Brouckaert)
    Generation and characterization of apo-soluble Guanylate Cyclase mice
  195. Vanhooren Valerie (27-Nov-2009; C. Libert)
    Glycomics of mammalian aging
  196. Crabbe Ellen (20-Nov-2009; K. Vleminckx)
    Identification and functional characterization of novel N-cadherin interacting proteins
  197. Willemarck Nicolas (20-Nov-2009; K. Vleminckx)
    Het Xenopus embryo als experimenteel platform voor de exploratie van nieuwe functies voor caspasen en tumorgeassocieerde de novo lipogenese
  198. Schoonooghe Steve (19-Oct-2009; J. Grooten)
    Multivalent and cross-reactive bispecific bibodies and tribodies for enhanced MUC1 tumour targeting
  199. Vanlaere Ineke (24-Sep-2009; C. Libert)
    Role of MMP-7 and IL-17A in acute systemic inflammation
  200. Demon Dieter (22-Jun-2009; P. Vandenabeele)
    Caspase-7: protease specificity activation and construction of a conditional knockout
  201. Tran Hong Thi (19-Jun-2009; K. Vleminckx)
    Development and use of novel transgenic lines to study Wnt signaling in the Xenopus embryo
  202. Huang Lieven (7-Jan-2009; R. Beyaert/P. De Baetselier)
    Characterization of EGF receptor targeting Nanobodies and ABIN for the treatment of EGF receptor-dependent tumours
  203. De Koker Stefaan (28-Oct-2008; N. Mertens/J. Grooten)
    Polyelectrolyte microcapsules for antibody delivery
  204. Huyghe Leander (10-Oct-2008; P. Brouckaert)
    Study of molecular and immunological factors that determine the sensitivity to the antitumor effect of Tumor Necrosis factor
  205. Bogaert Pieter (27-Mar-2008; J. Grooten)
    Transcriptome profiling of macrophage activation and inflammatory mediator expression in experimental mouse models of allergic pulmonary inflammation
  206. Jacobs Pieter (29-Feb-2008; N. Callewaert)
    Glycosylation and cell surface engineering in Pichia pastoris
  207. Vandewalle Cindy (28-Feb-2008; G.Berx & F. Van Roy)
    The role and mechanisms of SIP1 in the dedifferentiation of epithelial cancers
  208. Beekman Chantal - (21-Jan-2008; J.-C. Marine & F. Van Roy)
    A study of three putative players in the p53 pathway: Nucleostemin, Ptprv and TCTP
  209. Verschuere Veerle - (20-Dec-2007; K. Vleminckx)
    Analysis of the role of the p120 catenin subfamily in cell adhesion and cell migration during the early development of Xenopus laevis
  210. Loos Michaela - (7-Dec-2007; E. Remaut)
    Modulation of dendritic cell function through delivery of effector proteins by genetically modified Lactococcus lactis
  211. Coornaert Beatrice - (30-Nov-2007; R. Beyaert)
    MALT1 paracaspase-mediated regulation of the NF-kappaB inhibitory protein A20 in antigen receptor signaling
  212. Van Huynegem Karolien - (23-Nov-2007; E. Remaut)
    Genetically modified Lactococcus lactis as a tool in the prevention and healing of chemotherapy-induced intestinal mucositis
  213. Ovaere Petra - (5-Oct-2007; P. Vandenabeele)
    Identification of a Caspase-14 activating protease in murine skin extracts
  214. Verstrepen Lynn - (5-Oct-2007; R. Beyaert)
    Functional characterization of ABIN-3 and TAX1BP1 as negative regulators of NF-kappaB signaling
  215. Vande Walle Lieselotte - (28-Sep-2007; P. Vandenabeele)
    Role of the mitohondrial serine protease HtrA2/Omi in apoptosis
  216. Sips Patrick  (6-Jul-2007; P. Brouckaert)
    Functional analysis of soluble guanylate cyclase isoforms using mouse transgenics: cardiovascular effects of targeted mutagenesis of the alpha 1 subunit
  217. Vercammen Elisabeth  (22-Jun-2007; R. Beyaert)
    The secret life of Interleukin-1beta: molecular mechanisms involved in its production and biological activities
  218. Goethals An  (11-May-2007; P. Brouckaert)
    Studie in muismodellen van de mechanismen verantwoordelijk voor het antitumoraal effect van Tumor Necrosis Factor
  219. Van Lint Philippe  (20-apr-07, 16h30; C. Libert)
    The role of matrix metalloproteinases in specific inflammatory disorders
  220. Van Roy Maarten  (20-apr-07, 14h00;  C. Libert)
    New strategies to improve the safety and efficacy of a TNF/IFNgamma-based antitumor therapy
  221. Schepens Bert  (6-Oct-2006; R. Beyaert)
    The great escape: how Internal Ribosome Entry Sites can initiate translation of crucial mRNAs during hypoxia and mitosis
  222. De Smet Kris  (29-Sep-2006; R. Contreras)
    Studie van het celdoodproces in Candida albicans
  223. Schauvliege Reinout  (29-Sep-2006; R. Beyaert)
    Molecular mechanisms of LPS-induced pro-inflammatory signalling
  224. Delvaye Mieke  (28-Sep-2006; F. Van Roy & K. Vleminckx)
    Analysis of the morphogenetic role of known and novel cadherin-interacting proteins in Xenopus laevis
  225. Festjens Nele  (7-Jul-2006; P. Vandenabeele & X. Saelens)
    Characterization of molecular mechanisms associated with and involved in necrotic cell death
  226. Krysko Dmitri  (5-Jul-2006; K. D'Herde & P. Vandenabeele)
    Cell death: Initiation, propagation and clearance
  227. Laukens Debby  (29-Jun-2006; E. Remaut & P. Rottiers)
    Transcriptome profiling and genetic analysis to identify and characterize susceptibility genes for Crohn's disease
  228. Wullaert Andy  (5-May-2006; R. Beyaert)
    Effect of ABINs on intracellular signaling pathways involved in TNF-mediated liver injury
  229. Mahieu Tina  (31-Mrch-2006; C. Libert)
    A molecular analysis of the LPS resistance of the mouse species /Mus spretus
  230. Bultinck Jennyfer  (16-Mrch-06; P. Brouckaert)
    (Sub)cellular expression patterns and pathophysiological significance of INOS in inflammatory shock
  231. Goossens Steven  (24-Feb-06; F. Van Roy)
    Functional analysis of mouse alpha T-catenin
  232. Heirman Ingeborg  (1-Feb-06; J. Grooten)
    The tumor cell oxidative status and its interaction with eicosanoid synthesis in the control of tumor growth and malignant progression
  233. Vandepoele Karl  (22-Dec-2005; F. Van Roy)
    Genomic characterization and functional analysis of the novel NBPF gene family
  234. Termont Sofie  (16-Dec-2005; E. Remaut & P. Rottiers) 
    Optimization of Lactococcus lactis mediated mucosal delivery of cytokines
  235. Ryckaert Stefan  (9-Dec-2005; R. Contreras)
    Ontwikkeling van nieuwe toepassingen voor gist oppervlakte-expressie
  236. Soubry Adelheid  (6-Dec-2005; F. Van Roy)
    Analyse van de transcriptionele repressor Kaiso in humane tumoren en tijdens de celcyclus
  237. Denayer Tinneke  (2-Dec-05; F. Van Roy & K. Vleminckx)
    Functional study of the canonical Wnt pathway using transgenic tools in Xenopus laevis
  238. De Craene Bram  (19-may-05; F. Van Roy & G. Berx)
    The role of the Snail family of transcription factors in epithelial-mesenchymal transitions
  239. Van Belle Tom  (25-mar-05; J. Grooten)
    IL-15, a cytokine with direct action on CD8+ T cells, exerts an indirect action on TCR-stimulated CD4+ T cells
  240. Vanden Berghe Tom  (18-feb-05; P. Vandenabeele)
    Molecular interplay between apoptotic and necrotic cell death pathways
  241. Willems An   (28-jan-05; N. Mertens & J. Grooten)
    Tumorafhankelijke T cel activering met bispecifieke antilichamen: optimalisatie door protein-design
  242. Brouckaert Greet  (27-jan-05; P. Vandenabeele)
    Analysis of a cellular model for the recognition and phagocytosis of apoptotic and necrotic cells by macrophages
  243. Lamkanfi Mohamed  (10-nov-04; P. Vandenabeele)
    CARD proteins in apoptosis and inflammation
  244. Reekmans Rieka  (23-sep-04; R. Contreras)
    Transcriptional profiling of the Bax-responsive genes in S. cerevisiae.
  245. Vandenbroucke Klaas  (10-sep-04; E. Remaut, L. Steidler & P. Rottiers)
    Genetically modified Lactococcus lactis as in vivo delivery system for trefoil factors at the intestinal mucosa.
  246. Geysens Steven  (28-jun-04; R. Contreras)
    Klonering en karakterisering van fungale genen betrokken bij eiwit N-glycosylatie, kwaliteitscontrole en secretie.
  247. Vervecken Wouter  (28-jun-04; R. Contreras)
    Modificatie van de N-glycosylatiesyntheseweg van Aspergillus niger en Pichia pastoris.
  248. van Gurp Marjan (25-jun-04; P. Vandenabeele)
    Identification of protein-protein interactions in cell death signalling using the yeast two-hybrid system
  249. Staelens Jan  (31-mrt-04; C Libert)
    A molecular genetic analysis of the TNF resistance of the mouse species Mus spretus
  250. Bogaerts Sven  (13-feb-04; F. Van Roy)
    Characterization of a novel zinc finger protein ANC_2H01 (ZASC1)
  251. Pynaert Gwenda  (21-nov-03; J. Grooten)
    De regulerende werking van macrofagen op luchtweginflammatie in een muismodel voor astma 
  252. Vanpoucke Griet  (26-sep-03; F. Van Roy & G. Berx)
    The human alpha-catenins : regulation mechanisms controlling their expression
  253. Comijn Joke  (26-sep-03; F. Van Roy & G. Berx)
    SIP1-mediated transcriptional regulation of E-cadherin and identification of new SIP1 target genes
  254. Lippens Saskia  (12-sep-03; P. Vandenabeele & W. Declercq)
    Expression, regulation and processing of caspase-14 during epidermal differentiation
  255. Vanhalst Koen  (29-aug-03; F. Van Roy)
    Identification and functional analysis of new cadherin genes, possibly involved in murine brain development
  256. Buys Emmanuel  (23-may-03; P. Brouckaert)
    Target validation od soluble guanylate cyclase using conditional targeted mutagenesis in mice
  257. Carpentier Isabelle  (9-may-03; R. Beyaert)
    Molecular and functional characterization of the tumor necrosis factor receptor associated proteins TRAF1 and TRAF2
  258. Hostens Jeroen  (24-apr-03; P. Brouckaert)
    Onderzoek naar het mechanisme van de versterkende werking van IFN-gamma op het anti-tumoraal effect van TNF
  259. Janssens Sophie  (21-febr-03; R. Beyaert)
    Regulation of Interleukin-1 and endotoxin-induced responses by alternative splicing of MyD88
  260. Van Oekelen Dirk  (28-juni-02; G. Haegeman)
    The 5-HT2 receptor family: atypical regulation and functional insight through altered gene expression using antisense
  261. van Loo Geert  (14-juni-02; P. Vandenabeele)
    Apoptotic and necrotic cell death: cell death domain proteins and release of mitochondrial factors
  262. Strumane Kristin  (14-juni-02; F. Van Roy)
    E-cadherin-dependent differential gene expression in cancer cells reveals the novel E-cadherin-repressed oncogene hECRep1
  263. Callewaert Nico  (31-mei-02; R. Contreras) 
    Protein N-glycosylation : from yeast to man
  264. Vermeulen Linda  (17-mei-02; G. Haegeman)
    Studie van het moleculair mechanisme voor transcriptionele activering van NF- B p65 na inflammatorische stimulatie
  265. Bonné Stefan  (30-apr-02; F. Van Roy)
    Klonering en functionele karakterisering van het desmosomale eiwit plakophiline-3
  266. Janssens Barbara  (29-mrt-02; F. Van Roy)
    Study of two novel members of the human alpha-catenin family
  267. Wielockx Ben  (29-mrt-02; C. Libert & P. Brouckaert)
    De rol van proteasen en de identificatie van genen, coderend voor beschermende eiwitten, in TNF-geïnduceerde hepatitis en letale shock
  268. Hochepied Tino  (21-sep-01; P.Brouckaert & C.Libert)
    Onderzoek naar de rol van acute-fase proteïnen, in het bijzonder alfa1-zuur glycoproteïne, in muismodellen voor lokale en systemische inflammatie
  269. Van Huffel Sofie  (21-sep-01; F. Van Roy & R.Beyaert)
    Identificatie en functionele karakterisering van eiwitten die binden met het zinkvingereiwit A20
  270. Vanhauwe Jurgen  (15-jun-01; G. Haegeman & J. Leysen)
    Karakterisering van de ligand-bindings- en signaaltransductie-eigenschappen van humane dopamine D2- en D3-receptoren
  271. Francken Bart  (17-apr-01; G. Haegeman)
    Heterologous expression of G protein-coupled receptors and reconstituion of G protein coupling : h5-ht5A receptor in mammalian, insect, and bacterial cells
  272. De Wilde Gert  (10-jan-01; G. Haegeman)
    Studie van de ruimtelijke structuur van het TNFR-55 'death domain' en van de stroomafwaartse signalisatie naar MAP-kinasen
  273. Schotte Peter  (15-dec-00; R. Beyaert &F. Van Roy)
    Studie van caspasen en het activeringsmechanismen
  274. Van Craenenbroeck Kathleen  (21-jun-00; G. Haegeman)
    Onderzoek van induceerbare systemen voor heterologene genexpressie in zoogdiercellen
  275. Vanlandschoot Ann  (10-mei-00; F. Van Roy)
    Isolering en karakterisering van catenine- en cadherine-bindende eiwitten met mogelijke functies in signalisatiewegen en genregulatie
  276. Laroy Wouter  (9-mei-00; R. Contreras)
    Structuur-functie analyse van siaalzuur transfererende enzymen
  277. De Bosscher Karolien  (23-mrt-00; G. Haegeman)
    Onderzoek naar het mechanisme van Genrepressie door Glucocorticoïden
  278. Denecker Geertrui  (17-mrt-00; W. Fiers & P. Vandenabeele)
    Role of capases and mitochondria in apoptotic and necrontic cell death
  279. De Backer Marianne  (11-feb-00; R. Contreras)
    Identification of novel molecular targets for drugs against Candida albicans
  280. Dooms Hans  (28-jan-00; J. Grooten &F. Van Roy)
    Differentiële regulatie van apoptose en celdeling door interleukine-2 en -15 tijdens T-lymfocyt-antwoorden