The UGent TEM Expertise centre - site Tech Lane Ghent is embedded in the VIB Bioimaging Core that offers consultancy and access to different technologies for light- and electron microscopy and image processing. The core assists in experimental design, image acquisition and analysis. The main activities of the TEM Expertise centre site Technologiepark are TEM analysis of biomedical samples. The service portfolio consists of sample preparation by chemical fixation or high pressure freezing, semi-thin and ultrathin sectioning, immunostaining, blotting, support for image acquisition and interpretation. The core has experience with a broad range of biological samples going from plant tissue, mouse tissue, to eukaryotic cells, bacteria, viruses and more.