Transmission electron microscopy core facility


Contact : Riet De Rycke

Proeftuinstraat 86, 9000 Gent

Tel:+32 9 264 51 93 
Mobile: +32 472 81 64 39






General information on the TEM facility

The TEM-Core facility located on the campus ‘INW” of the UGent is providing expertise in the use and application of transmission electron microscopy to serve biological or biomedical research. The facility was established in 2003 and shares equipment of the Department of Biology.

Available equipment:

Jeol JEM1400plus, Leica ultramicrotome UC6, Leica ultramicrotome UC7 + FC7, Leica high-pressure freezer (EM-Pact), Leica AFS (automatic freeze substitution). The aim of the facility is to support research projects of all scientific groups of VIB1, Inflammation Research Center (IRC), including projects in cell biology, inflammation, glycobiology, virology, cancer biology, cell death, developmental biology, immunology…and VIB2, Plant Systems Biology (PSB), including projects dealing with cell cycle, cell death, gene regulation, plant microbes, root development, secondary metabolites… New approaches such as high-pressure freezing of various types of cells and tissues have been developed and standard TEM methods for morphological analysis and immuno-gold electron microscopy (single/double labeling) are provided. The benefit of such a TEM core facility for the ongoing research at the VIB has been demonstrated by the numerous high impact factor papers that relied on the addition of TEM data.
For more info and a complete list of publications visit


Publications since 2003 with contribution of IRC-PSB TEM-Core facility:

   Publications of this core facility in the UGent bibliography


1. D'Haeze W, De Rycke R, Mathis R, Goormachtig S, Pagnotta S, Verplancke C, Capoen W, Holsters M
Reactive oxygen species and ethylene play a positive role in lateral root base nodulation of a semiaquatic legume
P NATL ACAD SCI USA 100, 11789-11794, 2003

2. Rohde A, Morreel K, Ralph J, Goeminne G, Hostyn V, De Rycke R, Kushnir S, Van Doorsselaere J, Joseleau J-P, Vuylsteke M, Van Driessche G, Van Beeumen J, Messens E, Boerjan W
Molecular phenotyping of the pal1 and pal2 mutants of Arabidopsis thaliana reveals far-reaching consequences on phenylpropanoid, amino acid, and carbohydrate metabolism
PLANT CELL 16, 2749-2771, 2004

3. D'Haeze W, Glushka J, De Rycke R, Holsters M, Carlson RW
Structural characterization of extracellular polysaccharides of Azorhizobium caulinodans and importance for nodule initiation on Sesbania rostrata
MOL MICROBIOL 52, 485-500, 2004

4. De Smet I, Chaerle P, Vanneste S, De Rycke R, Inzé D, Beeckman T
An easy and versatile embedding method for transverse sections
J MICROSC-OXFORD 213, 76-80, 2004
5. Capoen W, Goormachtig S, De Rycke R, Schroeyers K, Holsters M
SrSymRK, a plant receptor essential for symbiosome formation
P NATL ACAD SCI USA 102, 10369-10374, 2005

6. Mathis R, Van Gijsegem F, De Rycke R, D'Haeze W, Van Maelsaeke E, Anthonio E, Van Montagu M, Holsters M, Vereecke D
Lipopolysaccharides as a communication signal for progression of legume endosymbiosis
P NATL ACAD SCI USA 102, 2655-2660, 2005

7. Vanstraelen M, Van Damme D, De Rycke R, Mylle E, Inzé D, Geelen D
Cell cycle-dependent targeting of a kinesin at the plasma membrane demarcates the division site in plant cells
Curr Biol 308-314, 2006

8. Van de Velde W, Pérez Guerra JC, De Keyser A, De Rycke R, Rombauts S, Maunoury N, Mergaert P, Kondorosi E, Holsters M, Goormachtig S
Aging in legume symbiosis. A molecular view on nodule senescence in Medicago truncatula
Plant Physiol 711-720, 2006

9. Vercammen D, Belenghi B, van de Cotte B, Beunens T, Gavigan JA, De Rycke R, Brackenier A, Inze D, Harris JL, Van Breusegem F
Serpin1 of Arabidopsis thaliana is a Suicide Inhibitor for Metacaspase 9
J Mol Biol 625-636, 2006

10. Van Damme D, Coutuer S, De Rycke R, Bouget FY, Inzé D, Geelen D
Somatic Cytokinesis and Pollen Maturation in Arabidopsis Depend on TPLATE, Which Has Domains Similar to Coat Proteins
Plant Cell 3502-3518, 2006

11. Goossens S, Janssens B, Vanpoucke G, De Rycke R, van Hengel J, Van Roy F
Truncated isoform of mouse alphaT-catenin is testis-restricted in expression and function
Faseb J 647-655, 2007

12. Goossens S, Janssens B, Bonné S, De Rycke R, Braet F, van Hengel J, Van Roy F
A unique and specific interaction between {alpha}T-catenin and plakophilin-2 in the area composita, the mixed-type junctional structure of cardiac intercalated discs
J Cell Sci 2126-2136, 2007

13. Fusaro AF, Bocca SN, Ramos RL, Barroco RM, Magioli C, Jorge VC, Coutinho TC, Rangel-Lima CM, De Rycke R, Inzé D, Engler G, Sachetto-Martins G
AtGRP2, a cold-induced nucleo-cytoplasmic RNA-binding protein, has a role in flower and seed development
Planta 1339-1351, 2007

14. Den Herder J, Vanhee C, De Rycke R, Corich V, Holsters M, Goormachtig S
Nod factor perception during infection thread growth fine-tunes nodulation
Mol Plant Microbe Interact 129-137, 2007

15. Leplé, JC., Dauwe, R., Morreel, K., Storme, V., Lapierre, C., Pollet, B., Naumann, A., Kang, KY., Kim, H., Ruel, K., Lefčbvre, A., Joseleau, JP., Grima-pettenati, J., De Rycke, R., Andersson-Gunnerĺs, S., Erban, A., Fehrle, I., Petit-Conil, M., Kopka, J., Polle, A., Messens, E., Sundberg, B., Mansfield, SD., Ralph, J., Pilate, G. and Boerjan, W.     Downregulation of cinnamoyl-coenzyme a reductase in poplar: multiple-level phenotyping reveals effects on cell wall polymer metabolism and structure. Plant Cell 19, 3669-3691, 2007

16. Takahashi, N, Vanlaere, I, de Rycke, R, Cauwels, A, Joosten, LA, Lubberts, E, van den Berg, WB, Libert, C.
IL-17 produced by Paneth cells drives TNF-induced shock
J Exp Med 205, 1755-1761, 2008

17. Den Herder G, De Keyser A, De Rycke R, Rombauts S, Van de Velde W, Clemente M R , Verplancke R, Mergaert P, Kondorosi E, Holsters M and Sofie Goormachtig
Seven in Absentia Proteins Affect Plant Growth and Nodulation in Medicago truncatula
Plant Physiology 148 369-382, 2008

18. Sklyarova, T, Bonne, S, D'hooge, P, Denecker, G, Goossens, S, de Rycke, R, Borgonie, G, Bösl, M, Van Roy, F, van Hengel, J.
Plakophilin-3-deficient mice develop hair coat abnormalities and are prone to cutaneous inflammation
J Invest Dermatol 128 1375-1385, 2008

19. Tanaka, H., Kitakura, S., De Rycke, R., De Groodt, R., and Friml, J.
Fluorescence Imaging-Based  Screen Identifies ARF GEF Component of Early Endosomal Trafficking.
Current biology 19, 391-397, 2009

20.    Capoen, W., Den Herder, J., Sun, J., Verplancke,C., De Keyser, A., De Rycke, R., Goormachtig,S., Oldroyd, G., and Holsters, M.
Calcium spiking patterns and the role of the calcium/calmodulin-dependent kinase CCaMK in lateral root base nodulation of Sesbania rostrata
The Plant Cell 10, 2009
21. De Koker, S, De Geest, BG, Singh, SK, De Rycke, R, Naessens, T, Van Kooyk, Y, Demeester, J, De Smedt, SC, Grooten, J.
Polyelectrolyte microcapsules as antigen delivery vehicles to dendritic cells: uptake, processing, and cross-presentation of encapsulated antigens
Angew Chem Int Ed Engl 48, 8485-8489, 2009.

22. Skirycz A, De Bodt S, Obata T, De Clercq I, Claeys H, De Rycke R, Andriankaja M, Van Aken O, Van Breusegem F, Fernie A R, and Inzé D Developmental stage specificity and the role of mitochondrial metabolism in the response of Arabidopsis leaves to prolonged mild osmotic stress1[w]
Plant Physiology 152:226-244, 2010

23. Perez Guerra JC, Coussens G, De Keyser A, De Rycke R, De Bodt S , Van De Velde W, Goormachtig S, and Holsters M. 
Comparison of developmental and stress-induced nodule senescence in Medicago truncatula
Plant Physiology, 2010

24. Wirawan E, Vande Walle1 L, Kristof K, Cornelis S, Claerhout S, Vanoverberghe I, Roelandt R, De Rycke R, Verspurten J, Declercq W, Agostinis P, Vanden Berghe T, S  Lippens and Vandenabeele P.
Caspase-mediated cleavage of Beclin-1 inactivates Beclin-1-induced autophagy and enhances apoptosis by promoting the release of proapoptotic factors from mitochondria
Cell Death and Disease, 2010

25. Feraru E, Paciorek T, Feraru M I, De Rycke R, De Groodt R, Kleine-Vehn J, and Friml J
The AP-3 adaptor complex mediates the biogenesis and function of the lytic vacuoles in Arabidopsis
The Plant Cell, 2010

26. Katrien Curvers, Hamed Seifi, Gre´gory Mouille, Riet de Rycke, Bob Asselbergh, Annelies Van Hecke, Dieter Vanderschaeghe, Herman Höfte, Nico Callewaert, Frank Van Breusegem, and Monica Höfte
Abscisic acid deficiency causes changes in cuticle permeability and pectin composition that influence tomato resistance to Botrytis cinerea 
Plant  Physiology, Vol. 154: 847-860 , 2010

27. Ruben Vanholme, John Ralph, Takuya Akiyama, Fachuang Lu, Jorge Rencoret Pazo, Hoon Kim, Jřrgen Holst Christensen, Brecht Van Reusel, Véronique Storme, Riet De Rycke, Antje Rohde, Kris Morreel, and Wout Boerjan
Engineering traditional monolignols out of lignin by concomitant F5H1-up- and COMT-down-regulation in Arabidopsis
Plant Journal, 2010

28. Guerfal, M, Ryckaert, S, Jacobs, PP, Ameloot, P, Van Craenenbroeck, K, Derycke, R, Callewaert, N.
The HAC1 gene from Pichia pastoris: characterization and effect of its overexpression on the production of secreted, surface displayed and membrane proteins
Microb Cell Fact, 2010.

29. Mc Guire, C, Volckaert, T, Wolke, U, Sze, M, De Rycke, R, Waisman, A, Prinz, M, Beyaert, R, Pasparakis, M, van Loo, G.
Oligodendrocyte-specific FADD deletion protects mice from autoimmune-mediated demyelination
J Immunol 185, 2010.

30. Nele Festjens, Erica Houthuys, Pieter Bogaert, Evelyn Plets, Anjana Batni, Bob Asselbergh, Eef Parthoens, Riet De Rycke, Monique Willart, Peggy Jacques, Dirk Elewaut, Peter Brouckaert, Bart Lambrecht, Kris Huygen, Nico Callewaert
M. bovis BCG SapM mutant as improved M. tb vaccine
EMBO Molecular Medicine, 2011

31. Remijsen, Q, Vanden Berghe, T, Wirawan, E, Asselbergh, B, Parthoens, E, De Rycke, R, Noppen, S, Delforge, M, Willems, J, Vandenabeele, P.
Neutrophil extracellular trap cell death requires both autophagy and superoxide generation
Cell Res, 2011.

32. Elena Babiychuk , Klaas Vandepoele , Josef Wissing , Miguel Garcia-Diaz , Riet De Rycke , Hana Akbari , Jérôme Joubčs , Tom Beeckman , Lothar Jänsch , Margrit Frentzen , Marc Van Montagu , Sergei Kushnir 
Plastid gene expression and plant development require a plastidic protein of the mitochondrial transcription termination factor family
PNAS, 2011

33. Katrijn Vannerum, Marie JJ Huysman, Riet De Rycke, Marnik Vuylsteke, Frederik Leliaert, Jacob Pollier, Ursula Lütz-Meindl, Jeroen Gillard, Lieven De Veylder, Alain Goossens, Dirk Inzé and Wim Vyverman
Transcriptional analysis of cell growth and morphogenesis in the unicellular green alga Micrasterias (Streptophyta), with emphasis on the role of expansin
BMC Plant Biology, 2011

34. Jifen Li, Steven Goossens, Jolanda van Hengel, Erhe Gao, Lan Cheng, Koen Tyberghein, Xiying Shang, Riet De Rycke, Frans van Roy, and Glenn Radice
Loss of αT-catenin alters the hybrid adhering junctions in the heart and leads to dilated cardiomyopathy and ventricular arrhythmia following acute ischemia
JCS, 2011

35. Dierendonck, M., De Koker, S., De Rycke, R., Bogaert, P., Grooten, J., Vervaet, C., Remon, J.P. & De Geest, B.G.
Single-step formation of degradable intracellular biomolecule microreactors.
ACS Nano, 2011

36. Katrijn Vannerum, Riet De Rycke, Jacob Pollier, Alain Goossens, Dirk Inzé, and Wim Vyverman Characterization of a RABE GTPase expressed during morphogenesis of the unicellular green alga Micrasterias denticulata (Zygnemophyceae, Streptophyta)
Journal of Phycology, 2011

37. Isolde Francis, Annick De Keyser, Philippe De Backer, Carmen Simón-Mateo,Jutta Kalkus, Ine Pertry, Wilson Ardiles-Diaz, Riet De Rycke, Olivier M. Vandeputte, Mondher El Jaziri, Marcelle Holsters, and Danny Vereecke
Deciphering pFiD188, the linear virulence plasmid of Rhodococcus fascians strain D188
Environmental Microbiology and Environmental Microbiology, 2012

38. Cleide Bomfeti, Paulo Avelar Ferreira, Teotônio Soares de Carvalho, Riet De Rycke, Fatima de Souza Moreira, Sofie Goormachtig, Marcelle HolstersNodule development on the tropical legume Sesbania virgata under flooded and nonflooded conditions Plant Biology, 2012

39. Leentje Jansen, Ianto Roberts, Riet De Rycke and Tom Beeckman
Phloem-associated auxin response maxima determine radial positioning of lateral roots in maize
Philos. Trans. R. Soc. B-Biol. Sci., 2012

44. M Schotsaert, T Ysenbaert, K Neyt, L I Ibańez, P Bogaert, B Schepens, B N Lambrecht, W Fiers and X Saelens
Natural and long-lasting cellular immune responses against influenza in the M2e-immune host    Mucosal Immunology, 2012 
TEM images in supplementary data

41. Roosmarijn E. Vandenbroucke, Eline Dejonckheere, Philippe Van Lint, Delphine Demeestere, Elien Van Wonterghem, Ineke Vanlaere, Leen Puimčge, Filip Van Hauwermeiren, Riet DeRycke, Conor Mc Guire, Cristina Campestre, Carlos López-Otin5, Patrick Matthys, Georges Leclercq, and Claude Libert
MMP8-dependent ECM cleavage at the blood-CSF barrier contributes to lethality during systemic inflammatory diseases
The Journal of Neuroscience, 2012

42. lena Feraru, Mugurel I. Feraru, Tomasz Paciorek, Riet De Rycke, Hirokazu Tanaka and Jiří Friml
BEX5/RabA1b Regulates trans-Golgi Network-to-Plasma Membrane Protein
Trafficking in Arabidopsis
The Plant Cell, 2012

43. Esther Hoste, Geertrui Denecker, Barbara Gilbert, Filip Van Nieuwerburgh, Leslie van der Fits, Bob Asselbergh, Riet de Rycke, Jean-Pierre Hachem, Dieter Deforce, Errol Prens, Peter Vandenabeele and Wim Declercq
Caspase-14 deficient mice are more prone to development of parakeratosis
Journal of Investigative Dermatology, 2012

44. MatyᚠFendrych, LukᚠSynek, Tamara Pečenková, Edita Janková-Drdová, Juraj Sekereš, Riet de Rycke, Moritz K Nowack, Viktor Žárský
Visualization of the Exocyst Complex Dynamics at the Plasma Membrane of Arabidopsis thaliana
Molecular Biology of the Cell, 2012   

45. Sandy Vanderauwera, Korneel Vandenbroucke, Annelies Inzé, Brigitte van de Cotte, Per Mühlenbock, Riet De Rycke, Naďra Naouar, Tim Van Gaever and Frank Van Breusegem
AtWRKY15 perturbation abolishes mitochondrial retrograde signaling that steers osmotic stress tolerance in Arabidopsis
PNAS, 2012

46. Kristiina Himanen, Tommaso Matteo Boccardi, Riet De Rycke, Ojola Patrick, Odeny and Mieke Van Lijsebettens
Is HUB1 a hub for plant fitness?
Plant Signaling & Behavior, 2012

47. Tomasz Nodzynski, Tomasz Nodzyński, Mugurel I. Feraru, Sibylle Hirsch, Riet De Rycke, Claudiu Niculaes, Wout Boerjan, Jelle Van Leene, Geert De  Jaeger, Steffen Vanneste, Jiří Friml
Retromer subunits VPS35A and VPS29 mediate prevacuolar compartment (PVC) function in Arabidopsis
Molecular Plant, 2013

48. Roosmarijn E. Vandenbroucke, Eline Dejonckheere, Filip Van Hauwermeiren, Sofie Lodens, Riet De Rycke, Elien Van Wonterghem, An Staes, Kris Gevaert, Carlos Lopez-Otin, Claude Libert.
Matrix metalloproteinase 13 modulates intestinal epithelial barrier integrity in inflammatory diseases by activating TNF
EMBO Molecular Medicine, 2013

49. Stéphanie Blockhuys, Bart Van Rompaye, Riet De Rycke, Kathleen Lambein,  Marc Bracke, Carlos De Wagter, Olivier De Wever.
Radiation-induced myosin IIA-dependent collagen type I matrix reorganization affects breast cancer cell death
Radiotherapy and Oncology, 2013

50. Hirokazu Tanaka, Saeko Kitakura, Hana Rakusová, Mugurel Feraru, Riet De Rycke, Stephanie Robert, Tatsuo Kakimoto, Jiří Friml
Cell polarity and patterning by PIN trafficking through early endosomal  compartments in Arabidopsis
PLOS Genetics, 2013

51. B. De Samber, K. A. C. De Schamphelaere, C. R. Janssen, B. Vekemans, R. De Rycke, G. Martinez-Criado, R. Tucoulou, P. Cloetens, L. Vincze
 Hard X-ray nanoprobe investigations of the subtissue metal distributions within Daphnia magna
Anal Bioanal Chem, 2013   

52. Thomas De Meyer, Dominique Eeckhout, Riet De Rycke, Sylvie De Buck, Serge  Muyldermans, Ann Depicker
Generation of VHH antibodies against the Arabidopsis thaliana seed  storage proteins
Plant Molecular Biology, 2013

53. Mouna Guerfal, Katrien Claes, Oskar Knittelfelder, Riet De Rycke, Sepp D Kohlwein, Nico Callewaert
Enhanced membrane protein expression by engineering increased  Intracellular Membrane production
Microbial Cell Factories, 2013

54. Zhang Zhiyue, Maji Samarendra, Antunes André, De Rycke Riet, Zhang Qilu,  Hoogenboom Richard, De Geest Bruno
Salt Plays a Pivotal Role in the Temperature-Responsive Aggregation and  Layer-by-Layer Assembly of Polymer-Decorated Gold Nanoparticles
Chemistry of Materials, 2013

55. Marijke Dierendonck, Stefaan De Koker, Riet De Rycke, Bruno De Geest
Just spray it – Next generation of electrostatic assembly
Soft Matter, 2013

56. Petra Nováková, Sibylle Hirsch, Elena Feraru, Ricardo Tejos, Tom Viaene, Riet De Rycke, Ringo van Wijk, Mugurel Feraru, Peter Grones, Ingo Heilmann, Teun Munnik, Marc CE Van Montagu,Jiří Friml
SAC domain phosphoinositide phosphatases at tonoplast mediate vacuolar function in Arabidopsis
PNAS, 2014

57. Fabiola Osorio, Simon J Tavernier, Eik Hoffmann, Yvan Saeys, Liesbet Martens, Jessica Vetters, Iris Delrue, Riet De Rycke, Eef Parthoens, Philippe Pouliot, Takao Iwawaki, Sophie Janssens, Bart N Lambrecht
The unfolded-protein-response sensor IRE-1α regulates the function of CD8alpha+ dendritic cells
Nature Immunology, 2014

58. Tongda Xu, Ning Dai, Jisheng Chen, Shingo Nagawa, Min Cao, Hongjiang Li, Zimin Zhou, Xu Chen, Riet De Rycke, Wuyi Wang, Alan M Jones, Jiří Friml, Sara E Patterson, Anthony B Bleecker, Zhenbiao Yang Cell surface
ABP1-TMK auxin sensing complex activates ROP GTPase signaling
Science, 2014

59. Bartel Vanholme, Ruben Vanholme, Halbay Turumtay, Geert Goeminne, Igor Cesarino, Florence Goubet, Kris Morreel, Jorge Rencoret, Vincent Bulone, Cortwa Hooijmaijers, Riet De Rycke, Godelieve Gheysen, John Ralph, Marc De Block, Frank Meulewaeter, Wout Bourjan
Accumulation of GlcNAc oligomers in the plant cell wall affects plant architecture in a dose-dependent and conditional manner
Plant Physiology, 2014

60. Marijke Dierendonck, Kaat Fierens, Riet De Rycke, Lien Lybaert, Samarendran Maji, Zhiyue Zhang, Oilu Zhang, Richard Hoogenboom, Bart N Lambrecht, Johan Grooten, Jean Paul Remon, Stefaan De Koker, Bruno G De Geest
Nanoporous hydrogen bonded polymeric microparticles: facile and economic production of cross presentation promoting vaccine carriers
Journal of Advanced Functional Materials, 2014

61. Satoshi Naramoto, Marisa S Otegui, Natsumaro Kutsuna, Riet De Rycke, Tomoko Dainobu, Michael Karampelias, Masaru Fujimoto, Elena Feraru, Daisuke Miki, Hiroo Fukuda, Akihiko Nakano,Jiří Friml
Insights into the localization and function of the membrane trafficking regulator GNOM ARF-GEF at the Golgi apparatus in Arabidopsis
The Plant Cell, 2014

62. Vandewynckel Yves-Paul, De Rycke Riet, Libbrecht Louis, Van Vlierberge Hans
Intestinal metaplasia in an orthotopic mouse model for hepatocellular carcinoma
Liver International, 2014

63. Charles Hachez, Timothée Laloux, Hagen Reinhardt, Riet De Rycke, Dirk Inzé, Michael R Blatt, Eugenia Russinova, François Chaumont
Arabidopsis SNAREs SYP61 and SYP121 coordinate the trafficking of plasma membrane aquaporin PIP2;7 to regulate the cell membrane water permeability
The Plant Cell, 2014

64. Marijke Dierendonck, Kaat Fierens, Riet De Rycke, Bart N Lambrecht, Johan Grooten, Jean Paul Remon, Bruno G De Geest, Stefaan De Koker
Nanoporous polyelectrolyte vaccine microcarriers - in vitro and in vivo evaluation
Journal of Controlled Release, 2014

65. Claudiu Niculaes, Kris Morreel, Hoon Kim, Fachuang Lu, Lauren McKee, Bart Ivens, Jurgen Haustraete, Bartel Vanholme, Riet De RYcke, Magnus Hertzberg, Jorg Fromm, Vincent Bulone, Andrea Polle, John Ralph, Wout Boerjan
PhenylCoumaran Bezylic Ether Reductase (PCBER) prevents accumulation of compounds formed under oxidative conditions in poplar xylem
The Plant Cell, 2014

66. Philippe De Groote, Mathias Fransen, Hong Thi Tran, Corinne Rösselet, Bram De Craene, Giel Tanghe, Kirsten Leurs, Barbara Gilbert, Riet De Rycke, CHris Guein, Pale Holland, Peter Vandenabeele, Kris Vleminckx, Saskia Lippens, Wim Declercq
A novel RIPK4-IRF6 connection is required to prevent epithelial fusions characteristic for popliteal pterygium syndromes
Cell Death and Differentiation, 2014

67. Filip Van Hauwermeiren F, Roosmarijn E Vandenbroucke, Elien Van Wonterghem, Linda Gryne, Riet De Rycke, N De Geest, G Kollias, B Hassan, Claude Libert
TNFR1-induced lethal inflammation is mediated by goblet and Paneth cell dysfunction
Mucosal Immunology, 2014

68. Yves-Paul Vandewynckel, Debby Laukens, Eliene Bogaerts, Annelies Paridaens, Anja Van den Bussche, Xavier Verhelst, Christophe Van Steenkiste, Benedicte Descamps, Chris Vanhove, Louis Libbrecht, Riet De Rycke, Bart N Lambrecht, Anja Geerts, Isabelle Colle, Sophie Janssens, Hans Van Vlierberghe
Modulation of the unfolded protein response impedes tumor cell adaptation to proteotoxic stress: a PERK for hepatocellular carcinoma therapy
Hepatology International, 2014

69. Lien Lybaert, Elly De Vlieghere, Riet De Rycke, Nane Vanparijs, Olivier De Wever, Stefaan De Koker, Aaron Esser-Kahn, Bruno G De Geest
Bio-hybrid tumor cell-templated capsules: a generic formulation strategy for tumor associated antigens in view of anti-cancer immune-therapy
Journal of Advanced Functional Materials, 2014

70. Thomas De Meyer, Bram Laukens, Jonah Nolf, Els Van Lerberge, Riet De Rycke, Ans Debeuckelaer, Sylvie De Buck, Nico Callewaert, Ann Depicker
Comparison of VHH-Fc antibody production in Arabidopsis thaliana, Nicotiana benthamiana and Pichia pastoris
Plant Biotechnology Journal, 2014

71. Peter Grones, Xu Chen, Sibu Simon, Walter A. Kaufmann, Riet De Rycke, Tomasz Nodzynski, Eva Zažímalová and Jiří Friml
Auxin binding pocket of ABP1 is crucial for its gain-of-function cellular and developmental roles
Journal of Experimental Botany, 2015

72. Liesbeth Vercruyssen, Vanesa B. Tognetti, Nathalie Gonzalez, Judith Van Dingenen, Liesbeth De Milde, Agnieszka Bielach, Riet De Rycke, Frank Van Breusegem, and Dirk Inzé
Growth regulating factor5 stimulates Arabidopsis Chloroplast division, photosynthesis and leaf longevity
Plant Physiology, 2015

73. Niemiec MJ , De Samber B , Garrevoet J , Vergucht E , Vekemans B , De Rycke R , Björn E, Sandblad L , Wellenreuther G , Falkenberg, G , Cloetens P , Vincze L & Urban CF
Trace element landscape of resting and activated human 2 neutrophils on the sub-micrometer level
Metallomics, 2015

74. Simon Devos, Laurence Van Oudenhove, Stephan Stremersch, Wouter Van Putte, Riet Derycke, Gonzalez Van Driessche, Jolien Vitse, Koen Raemdonck and Bart Devreese
The effect of imipenem and diffusible signaling factors on the secretion of outer membrane vesicles and associated Ax21 proteins in Stenotrophomonas maltophilia
 Frontiers in microbiology, 2015

75. Zhiyue Zhang, Katleen Van Steendam, Riet De Rycke, Samarendra Maji , Lieve Balcaen, Glenn Vanluchene, Frank Vanhaecke, Dieter Deforce, Richard Hoogenboom, Bruno G. De
Tailoring Cellular Uptake of Gold Nanoparticles via the Hydrophilic-to-Hydrophobic Ratio of their (co)polymer coating
Journal of Advanced Functional Materials, 2015

76. Kim Baert; Bruno G De Geest; Riet De Rycke; André  B da Fonseca Antunes; Bert Devriendt; Eric Cox
β-glucan microparticles targeted to epithelial APN as oral antigen delivery system
Journal of Controlled Release, 2015

77. Kasmi, Sabah; Louage, Benoit; Nuhn, Lutz; Van Driessche, Aleaxandra; Van Deun, Jan; Karalic, Izet; Risseeuw, Martijn; Van Calenbergh, Serge; Hoogenboom, Richard; De Rycke, Riet; De Wever, Olivier; Hennink, Wim; De Geest, Bruno
Transiently responsive block copolymer micelles based on HPMA engineered with hydrolysable ethylcarbonate side chains
Biomacromolecules, 2015

78. Hui Li, Kaat Fierens, Zhiyue Zhang, Nane Vanparijs, Martijn Schuijs, Katleen Van Steendam, Natŕlia Feiner Gracia, Riet De Rycke, Thomas De Beer, Ans De Beuckelaer, Stefaan De Koker, Dieter Deforce, Lorenzo Albertazzi, Johan Grooten, Bart N. Lambrecht,and Bruno G. De Geest
Spontaneous Protein Adsorption on Graphene Oxide Nanosheets Allows Efficient Intracellular Vaccine Protein Delivery
ACS Applied materials & Interfaces, 2016

79. Gilles Brackman, Koen Breyne, Riet De Rycke, Arno Vermote, Filip Van Nieuwerburgh, Evelyne Meyer, Serge Van Calenbergh & Tom Coenye
The Quorum Sensing Inhibitor Hamamelitannin Increases Antibiotic Susceptibility of Staphylococcus aureus Biofilms by Affecting Peptidoglycan Biosynthesis and eDNA Release
Scientific reports, 2016

80. Z. Zhang, B. Schepens, L. Nuhn, X. Saelens, M. Schotsaert, N. Callewaert, R. De Rycke, Q. Zhang, S. Moins, S. Benali, L. Mespouille, R.Hoogenboom and B. G. De Geest
Influenza-binding sialylated polymer coated gold nanoparticles prepared via RAFT polymerization and reductive amination
ChemicalCommunications, 2016

81. Van Dingenen J., De Milde L., Vermeersch M., Maleux K., De Rycke R., De Bruyne M., Storme V., Gonzalez N., Dhondt S. and Inzé D.
Chloroplasts are central players in sugar-induced leaf growth
Plant Physiology, 2016

82. Daan van der Zwaag , Nane Vanparijs , Sjors Wijnands , Riet De Rycke ,Bruno de Geest
Super Resolution Imaging of Nanoparticles Cellular Uptake and Trafficking
ACS Applied Materials & Interfaces, 2016

83. Sriram Balusu, Elien Van Wonterghem, Riet De Rycke, Koen Raemdonck, Stephan Stremersch, Kris Gevaert, Marjana Brkic, Delphine Demeestere, Valerie Vanhooren, An Hendrix, Claude Libert and Roosmarijn E. Vandenbroucke
Extracellular vesicles from the choroid plexus mediate blood-brain communication during peripheral inflammation
EMBO Molecular Medicine, 2016

84. Betti C., Vanhoutte I., Coutuer S., De Rycke R., Mishev K., Vuylsteke M., Aesaert S., Rombaut D., Gallardo R., De Smet F., Xu J., Van Lijsebettens, M., Van Breusegem F., Inzé D., Rousseau F., Schymkowitz J. and Russinova E
Sequence-specific protein aggregation generates defined protein knockdowns in plants
Plant Physiology, 2016

85. Simon S., Skůpa P. , Viaene T., Zwiewka M., Tejos R., Klíma P., Čarná M., Rolčík J., De Rycke R., Moreno I., Dobrev P.I., Orellana A., Zažímalová E. and Friml J.
PIN6 auxin transporter at endoplasmic reticulum and plasma membrane mediates auxin homeostasis and organogenesis in Arabidopsis
New Phytologist, 2016

86. Beata Orman-Ligeza, Boris Parizot, Riet De Rycke, Ana Fernandez, Ellie Himschoot, Frank Van Breusegem, Malcolm Bennett, Claire Perilleux, Xavier Draye and Tom Beeckman
RBOH-mediated ROS production facilitates lateral root emergence in Arabidopsis
Development, 2016

87. Zhiyue Zhang, Samarendra Maji, André B. da Fonseca Antunes, Riet De Rycke, Richard Hoogenboom, Bruno G. De Geest
Salt-Driven Deposition of Thermoresponsive Polymer-Coated Metal Nanoparticles on Solid Substrates
Angew Chem Int Ed Engl, 2016

88. Tim Pieters, Steven Goossens, Lieven Haenebalcke, Vanessa Andries, Agata Stryjewska, Riet De Rycke, Kelly Lemeire, Tino Hochepied, Danny Huylebroeck, Geert Berx, Marc P Stemmler, Dagmar Wirth, Jody J Haigh, Jolanda van Hengel, Frans van Roy
p120 Catenin-Mediated Stabilization of E-cadherin is Essential for Primitive Endoderm Specification
PLOS Genetics, 2016

89. Ranhua Xiong, Freya Joris, Sayuan Liang, Riet De Rycke,⊥ Saskia Lippens, Jo Demeester, Andre Skirtach, Koen Raemdonck, Uwe Himmelreich, Stefaan C. De Smedt and Kevin Braeckmans
Cytosolic Delivery of Nanolabels Prevents Their Asymmetric Inheritance and Enables Extended Quantitative in Vivo Cell Imaging
NANO letters, 2016

90. Björn De Samber, Maria J. Niemiec, Brecht Laforce, Jan Garrevoet, Eva Vergucht, Riet De Rycke, Peter Cloetens, Constantin F. Urban , Laszlo Vincze
Probing Intracellular Element Concentration Changes during Neutrophil Extracellular Trap Formation Using Synchrotron Radiation Based X-Ray Fluorescence
PLoS One, 2016

91. Tim Van Damme, Thatjana Gardeitchik, Miski Mohamed, Sergio GuerreroCastillo, Peter Freisinger, Brecht Guillemyn,  Ariana Kariminejad, Daisy Dalloyaux, Sanne van Kraaij, Dirk J. Lefeber, Delfien Syx,  Wouter Steyaert, Riet De Rycke, Alexander Hoischen,  Erik-Jan Kamsteeg,  Sunnie Y. Wong, Monique van Scherpenzeel,  PaymanJamali, Ulrich Brandt, Leo N ijtmans, G. Christoph Korenke, Brian H.Y. Chung,Christopher C.Y. Mak, Ingrid Hausser, Uwe Kornak, Björn Fischer-Zirnsak, Tim M.Strom, Thomas Meitinger, Yasemin Alanay, Gulen E. Utine, Peter K.C. Leung, Siavash Ghaderi-Sohi, Paul Coucke,  Sofie Symoens, Anne De Paepe, Christian Thiel, Tobias B. Haack, Fransiska Malfait, Eva Morava, Bert Callewaert, Ron A. Wevers
Mutations in ATP6V1E1 or ATP6V1A Cause Autosomal Recessive Cutis Laxa
American Journal of Human Genetics, 2017

92. Alejandro Estrada-Cuzcano, Shaun Martin, Teodora Chamova, Matthis Synofzik, Dagmar Timmann, Tine Holemans, Albena Andreeva, Jennifer Reichbauer, Riet De Rycke, Dae-In Chan, Sarah van Veen, Jean Samuel, Ludger Schöls, Thorsten Pöppe, Danny Mollerup Sřrensen, Bob Asselbergh, Christine Klein, Stephan Zuchner, Albena Jordanova1, Peter Vangheluwe, Ivailo Tournev, Rebecca Schüle
Loss-of-function mutations in the ATP13A2/PARK9 gene cause complicated hereditary spastic paraplegia (SPG78)
Brain, 2017