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 Welcome to the website of the Inflammation Research Center

a VIB-UGent Department

Director: Prof. Dr. Bart LAMBRECHT

The Inflammation Research Center (IRC or 'Inflammatie-researchcentrum') is active within VIB and Ghent University.

Inflammation is the first response of the immune system to infection or tissue injury, leading to protection of the body against these insults. However, chronic inflammation forms the basis of several diseases such as asthma, rheumatoid arthritis, colitis, multiple sclerosis and even certain forms of cancer.

The IRC labs study the molecular mechanisms of inflammation. At the heart of this research is the investigation of molecular signaling pathways in inflammatory cells and structural cells of the skin, lung, gut and brain. We particularly focus on NF-κB, ER stress and cell death pathways and study how these are altered by disease. Research is multidisciplinary with molecular biologists, cell biologists, and bioinformaticians collaborating with clinicians.

It is the IRC's ambition to translate our basic research into innovative ways for diagnosis and therapy of human inflammatory diseases. To complement the mechanism-oriented research, IRC therefore actively supports R&D of innovative molecular biotechnological platforms. These tools offer new approaches to study the mechanisms of inflammation, and form the essential basis for novel diagnostics and therapeutics. The IRC has a track record of advanced translational biotechnology research, with several products now in clinical development. These products will soon benefit patients with Crohn's disease, allergies and lysosomal storage diseases.


      Follow the IRC also on: Twitter, Facebook and LinkedIn


IRC - VIB-UGent Research Units


Mathieu BERTRAND
Team leader


Geert BERX

Group leader


Rudi BEYAERT

Group leader


Wim DECLERCQ
Team leader


Dirk ELEWAUT
Group leader


Martin GUILLIAMS

Team leader


Hamida HAMMAD

Group leader


Sophie JANSSENS
Team leader


Bart LAMBRECHT

Director & Group leader


Mohamed LAMKANFI
Group leader


Claude LIBERT

Group leader


Yvan SAEYS

Group leader


Savvas SAVVIDES

Group leader


Peter VANDENABEELE

Group leader


Roos VANDENBROUCKE

Team leader


Jo VAN GINDERACHTER
Group leader


Geert van LOO
Group leader


Frans VAN ROY

Group leader



IRC - UGent Labs

VIB Medical Biotechnology Center Research Units (located in the IRC)


Helix sculpture

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