» Home 
Print this pageEmail this page URLConvert this page to PDF

Welcome to the website of the Inflammation Research Center

a VIB-UGent Department

Director: Prof. Dr. Bart LAMBRECHT

The Inflammation Research Center (IRC or 'Inflammatie-researchcentrum') is active within VIB and Ghent University.

Inflammation is the first response of the immune system to infection or tissue injury, leading to protection of the body against these insults. However, chronic inflammation forms the basis of several diseases such as asthma, rheumatoid arthritis, colitis, multiple sclerosis and even certain forms of cancer.

The IRC labs study the molecular mechanisms of inflammation. At the heart of this research is the investigation of molecular signaling pathways in inflammatory cells and structural cells of the skin, lung, gut and brain. We particularly focus on NF-κB, ER stress and cell death pathways and study how these are altered by disease. Research is multidisciplinary with molecular biologists, cell biologists, and bioinformaticians collaborating with clinicians.

It is the IRC's ambition to translate our basic research into innovative ways for diagnosis and therapy of human inflammatory diseases. To complement the mechanism-oriented research, IRC therefore actively supports R&D of innovative molecular biotechnological platforms. These tools offer new approaches to study the mechanisms of inflammation, and form the essential basis for novel diagnostics and therapeutics. The IRC has a track record of advanced translational biotechnology research, with several products now in clinical development. These products will soon benefit patients with Crohn's disease, allergies and lysosomal storage diseases.



IRC - VIB Research Units


Geert BERX


Rudi BEYAERT


Nico CALLEWAERT


Bart LAMBRECHT
Director


Claude LIBERT


Xavier SAELENS


Peter VANDENABEELE


Frans VAN ROY


IRC - VIB Research Teams


Mathieu BERTRAND


Wim DECLERCQ


Hamida HAMMAD


Sophie JANSSENS


Geert van LOO


IRC - UGent Labs


Peter BROUCKAERT


Johan GROOTEN


Kris VLEMINCKX


Helix sculpture

Best viewed with Firefox: